(R)-3-Amino-4,4-diphenylbutyric acid

(R)-3-Amino-4,4-diphenylbutyric acid - Names and Identifiers

Name	(R)-3-Amino-4,4-diphenyl-butyric acid-HCl
Synonyms	H-D-b-HoPhe(4-phenyl)-OH·HCl H-D-BETA-HOPHE(4-PHENYL)-OH HCL H-D-β-HoAla(4,4-Diphenyl)-OH.HCl (R)-3-Amino-4,4-diphenylbutyric acid (R)-3-Amino-4,4-diphenyl-butyric acid-HCl 4-PHENYL-D-BETA-HOMOPHENYLALANINE HYDROCHLORIDE (R)-3-AMINO-4,4-DIPHENYL-BUTYRIC ACID HYDROCHLORIDE (R)-4-([1,1'-Biphenyl]-4-yl)-3-aMinobutanoic acid hydrochloride (betaR)-beta-Amino-gamma-phenylbenzenebutanoic acid hydrochloride
CAS	332062-03-0

(R)-3-Amino-4,4-diphenylbutyric acid - Physico-chemical Properties

Molecular Formula	C16H18ClNO2
Molar Mass	291.77
Storage Condition	Sealed in dry,Room Temperature

(R)-3-Amino-4,4-diphenylbutyric acid - Introduction

(R)-3-Amino-4,4-diphenyl-butyric acid-HCl ((R)-3-Amino-4,4-diphenyl-butyric acid-HCl) is an organic compound with the chemical formula C18H20ClNO2. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White or off-white solid
-Solubility: Soluble in water, soluble in organic solvents such as alcohols and chloroform
-Melting point: about 160-165°C

Use:
- (R)-3-Amino-4,4-diphenyl-butyric acid-HCl is a chiral compound, commonly used as a chiral ligand or reagent in organic synthesis.
-It is often used in the preparation of chiral drugs in drug synthesis.

Preparation Method:
-A common preparation method is through the synthesis of butyric acid and subsequent reaction:
1. First, benzyl cyanide and phenyl formaldehyde reaction synthesis of phenyl methyl hydrazine.
2. Then, it is reduced to benzhydrazine by hydrogenation.
3. In the presence of nitrobenzene, benzhydrazine reacts with γ-nitrobutyric acid to generate nitrohydrazine.
4. Finally, through heating and reduction, the nitrohydrazine is reduced to (R)-3-Amino-4,4-diphenyl-butyric acid-HCl.

Safety Information:
- (R)-3-Amino-4,4-diphenyl-butyric acid-HCl has limited safety evaluation, so standard laboratory safety measures should be taken during use or operation.
-Avoid contact with skin and eyes, wear protective gloves and goggles if necessary.
-Should be handled in a well-ventilated area to avoid inhalation or ingestion of substances.
-In case of misuse or discomfort, seek medical attention and bring information about the compound.

Please note that the safety data sheet of the compound and the instructions for use of related materials should be carefully read and followed before use.

Last Update：2024-04-09 21:01:54